proximal neuropathy exercises

click to enable zoom
Loading Maps
We didn't find any results
open map
Your search results

proximal neuropathy exercises

Oluseun Olufade, MD, is a board-certified orthopedist. This increases the size of the tunnel and decreases pressure on the nerve. Repeat: 2 repetitions on each leg /2 times a day, Hold chair or table with one hand, then one fingertip, then no hands; then do exercise with eyes closed, if steady. WebPerform these exercises seated. Sometimes, treating the underlying condition can stop the progression of neuropathy. What is the most common type of neuropathy? Mayo Clinic is a not-for-profit organization. This site complies with the HONcode standard for trustworthy health information: verify here. National Institute of Neurological Disorders and Stroke. Some types of neuropathies can be cured. Numbness or reduced ability to feel pain or temperature changes, Extreme sensitivity to touch for some people, even a bedsheet's weight can be painful, Serious foot problems, such as ulcers, infections, and bone and joint damage, A lack of awareness that blood sugar levels are low (hypoglycemia unawareness), Drops in blood pressure when rising from sitting or lying down that may cause dizziness or fainting (orthostatic hypotension), Slow stomach emptying (gastroparesis), causing nausea, vomiting, sensation of fullness and loss of appetite, Changes in the way the eyes adjust from light to dark or far to near, Problems with sexual response, such as vaginal dryness in women and erectile dysfunction in men, Difficulty rising from a sitting position, Numbness or tingling in the hand or fingers, Weakness in the hand that may result in dropping things, Weakness causing difficulty lifting the front part of the foot (foot drop), A cut or sore on your foot that is infected or won't heal, Burning, tingling, weakness or pain in your hands or feet that interferes with daily activities or sleep, Changes in digestion, urination or sexual function. Accessed Jan. 10, 2020. Stand with your feet hip-width apart and your hands on your hips. Hold: 15-20 seconds on each leg Follow the same steps as you lift your right leg to the side of your body and then behind you. Symptomatic treatment is important, but it does not heal the myelin or the nerve and it does not prevent neuropathy from worsening. It involves a close relationship between the nervous system, soft tissues, and proprioceptors (1, 2). Shift your weight onto your left foot and lift your right foot a few inches off of the ground. Hold: 5-10 seconds Diabetes Care. include protected health information. Rotator Cuff and Shoulder Conditioning Program, Ulnar Nerve Entrapment at the Elbow (Cubital Tunnel Syndrome). Flat electrodes are placed on the skin and a low electric current stimulates the nerves. doi:10.1212/WNL.0000000000012618, Lin X, Chen C, Liu Y, Peng Y, Chen Z, Huang H, Xu L. Peripheral nerve conduction and sympathetic skin response are reliable methods to detect diabetic cardiac autonomic neuropathy. Some people have mild symptoms. Aim for 150 minutes of moderate or 75 minutes of vigorous aerobic activity a It can take weeks or longer before you notice the effects of treatment, but do not be discouraged. Your health care provider will figure out the best target range for you based on factors including your age, how long you've had diabetes and your overall health. the unsubscribe link in the e-mail. Some doctors think that exercises to help the ulnar nerve slide through the cubital tunnel at the elbow and the Guyon's canal at the wrist can improve symptoms. It also often affects nerves on both sides of the body symmetrically. They happen more often when the elbow is bent, such as when driving or holding the phone. Do I need tests to confirm the cause of my symptoms? Depending on the affected nerves, diabetic neuropathy symptoms include pain and numbness in the legs, feet and hands. This article will discuss the types of neuropathy, their symptoms, and treatment. Disorders of peripheral nerves. Does anything seem to improve your symptoms? Accessed March 25, 2019. These tests can determine how well the nerve is working and help identify where it is being compressed. Lidocaine patches are another treatment you apply to your skin that might offer pain relief. Stand on one foot lifting the other heel off the floor, standing on your toes (as you strengthen your muscles, try to alternate your heels as shown in the picture below). In some cases, it may be harder to move your fingers in and out, or to manipulate objects. If you find yourself feeling depressed, it may help to talk to a counselor or therapist. Peripheral neuropathy causes. All rights reserved. 2 repetitions on each leg /2 times a day. What are some things that can cause neuropathy symptoms to flare up? All rights reserved. information is beneficial, we may combine your email and website usage information with Inflammatory disease is a common culprit. Peripheral neuropathy treatments. It is less common For example, you may find relief from acetaminophen (Tylenol, others) or ibuprofen (Advil, Motrin IB, others) or a skin patch with lidocaine (a numbing substance). Topical treatments. Start Here. There are three main types of exercises ideal for people with peripheral neuropathy: aerobic, bal Philadelphia, Pa.: Elsevier; 2018. https://www.clinicalkey.com. For example, being able to detect uneven ground can tell your body to adapt its center of gravity to balance itself. It affects the feet and legs first, followed by the hands and arms. Foot problems, including sores that don't heal, ulcers and even amputation, are common complications of diabetic neuropathy. Gradually pull the toes and ankle up as high as you can. Structures that may compress the nerve such as the medial epicondyle and ulnar collateral ligament are also shown. If you use a computer frequently, make sure that your chair is not too low. Reproduced from J Bernstein, ed: Musculoskeletal Medicine. This content does not have an English version. Healthline Media does not provide medical advice, diagnosis, or treatment. If youre looking to take your fitness routine up a notch or make your day-to-day living easier, youll want to give proprioception training a try. http://www.ninds.nih.gov/disorders/peripheralneuropathy/detail_peripheralneuropathy.htm. To make this exercise more challenging position your feet closer to your body. Using a firm chair with armrests, position your feet in a split stance with one foot at the base of the chair and the other foot placed comfortably in front and slightly out to the side. Peripheral neuropathy fact sheet. Loosely wrapping a towel around your arm with tape can help you remember not to bend your elbow during the night. See the 12. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Management of diabetic neuropathy. While seating on the front half of a chair place both feet flat on the floor. The serotonin and norepinephrine reuptake inhibitor duloxetine (Cymbalta, Drizalma Sprinkle) and the extended-release antidepressants venlafaxine (Effexor XR) and desvenlafaxine (Pristiq) also might ease the pain of peripheral neuropathy caused by diabetes. Keep your elbow straight at night when you are sleeping. While standing at the kitchen counter, place two finger tips on the counter. Even as an experienced athlete, you can still benefit from proprioceptive training. Accessed Nov. 11, 2021. How is proprioception related to balance? Mayo Clinic is a not-for-profit organization. Standards of medical care in diabetes 2021. Guillain-Barrsyndrome fact sheet. Your health care provider typically checks your: Along with the physical exam, your health care provider may perform or order specific tests to help diagnose diabetic neuropathy, such as: Diabetic neuropathy has no known cure. As the nerve enters the hand, it travels through another tunnel (Guyon's canal). In this operation, the ligament roof of the cubital tunnel is cut and divided. other information we have about you. Serotonin and norepinephrine reuptake inhibitors (SNRIs) are another type of antidepressant that may help with nerve pain and have fewer side effects. Is this condition temporary or long lasting? Because this condition causes severe facial weakness and can appear like a stroke, it is important to see a doctor who can determine whether there is a medical emergency. Although steroids, such as cortisone, are very effective anti-inflammatory medicines, steroid injections are generally not used to treat cubital tunnel syndrome because there is a risk of damage to the nerve. Proximal neuropathy A rare type of nerve damage is proximal neuropathy. Why is proprioception important in sports and fitness? Tip: For beginners, try this move without the loop band. In: Ferri's Clinical Advisor 2022. After discussing your symptoms and medical history, your doctor will examine your arm and hand to determine which nerve is compressed and where it is compressed. The nerve can be moved to lie under the skin and fat but on top of the muscle (subcutaneous transposition); within the muscle (intermuscular transposition); or under the muscle (submuscular transposition). information highlighted below and resubmit the form. Anyone who has diabetes can develop neuropathy. Balance, in particular, is emerging as an important element for the elderly. Proprioception, also known as kinesthesia, is the ability to sense and freely move your body and limbs in your external environment. There are no treatments that can specifically heal a nerve, but sometimes you can use physical therapy to improve your motor function and avoid injuries by learning to adapt and maximize your abilities. Can Tingling in the Hands and Feet Be a Symptom of Diabetes? These medications affect nerve activity in a way that can subdue the pain. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Accessed Dec. 17, 2021. What treatments are available, and which do you recommend? They may also ask about your work, your activities, and what medications you are taking. To prevent injury, your body adjusts, stabilizing your foot and ankle in response to the feedback picked up by your lower limb proprioceptors. Nerve conduction studies can also determine whether the compression is also causing muscle damage. If you have a foot injury or sore, stick with exercise that doesn't require putting weight on your injured foot. Autonomic neuropathy causes different symptoms that may include diarrhea, constipation, urinary incontinence, lightheadedness, flushing, and more. The best way to prevent peripheral neuropathy is to manage medical conditions that put you at risk, such as diabetes, alcoholism or rheumatoid arthritis. Hold: 15-20 seconds on each leg Guillain-Barr is also known to involve the muscles that control breathing, which can cause a respiratory emergency. Autonomic neuropathy is associated with severe diabetes and systemic illnesses, such as kidney failure and cancer. What side effects can I expect from treatment? AskMayoExpert. In: Ferri's Clinical Advisor 2022. AskMayoExpert. Center your chest over the straight leg, and slowly straighten your back until you feel a muscle stretch in the back of your leg. 2023 Dotdash Media, Inc. All rights reserved. Diabetic neuropathy. Often, these symptoms come and go. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Medications that are often used to control neuropathic pain include antidepressants and antiepileptic drugs (AEDs, which typically are used to treat nerve cell activity causing seizures). For those of us contemplating how we can be our healthiest selves, Mike Foxworth, a FPN member and member of the Metro DC Area Support Group, shares how exercising with a group helps him keep his fitness, On July 9, 2018, the Federal Drug Administration (FDA) held a public forum focusing on the patients perspective on drug development for chronic pain. To protect the health of your feet: Mayo Clinic does not endorse companies or products. Lift the toes and Does anything seem to improve your symptoms? Mononeuropathy may lead to: Call your health care provider for an appointment if you have: The American Diabetes Association (ADA) recommends that screening for diabetic neuropathy begin immediately after someone is diagnosed with type 2 diabetes or five years after diagnosis with type 1 diabetes. The most common place for compression of the nerve is behind the inside part of the elbow. All material on this website is protected by copyright. Are there treatments available, and which do you recommend? Review/update the Balance exercises are an important part of staying active and healthy. It recommends walking shorter distances, cycling, swimming, and chair exercises in a moderate climate over running, jumping, and lifting weights, particularly in For more balance, stretch your arms out to your sides. Signs and symptoms of peripheral neuropathy are often worse at night, and may include: The autonomic nervous system controls blood pressure, heart rate, sweating, eyes, bladder, digestive system and sex organs. You should feel a muscle stretch in the calf of your back leg. What's challenging about managing your diabetes? Cutsforth-Gregory (expert opinion). Explore Mayo Clinic studies testing new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition. Hold chair or table with one hand, then one fingertip, then no hands; then do exercise with eyes closed, if steady. In: Bradley and Daroff's Neurology in Clinical Practice. Finally, you learn to dribble, run, and shoot all while paying attention to the game around you. With the ball of your right foot touching the ground and heel up, lower your right leg until your thigh is perpendicular to the ground and your right knee is at a 90-degree angle. WebProximal symmetrical pelvic > shoulder girdle weakness Pseudohypertrophy of muscles: Peripheral neuropathy Delayed relaxation of ankle jerks Myoedema (mounding of muscle when firmly palpated) Hyperthyroid myopathy: Affects 52%82 % of patients with hyperthyroidism: Symmetrical proximal weakness, atrophy, some distal muscle Follow your health care provider's recommendations for good foot care. Castro MR (expert opinion). When your bend your elbow, the ulnar nerve must stretch around the boney ridge of the medial epicondyle. This is especially important for older adults, who may be at an increased risk of, You may already know that yoga is a great way to get moving, but could it also help with Parkinson's symptoms? Do I need to see a certified diabetes care and education specialist, a registered dietitian, or other specialists? First, you learn to dribble the ball on the spot. You may then be referred to a doctor trained in nervous system disorders (neurologist). privacy practices. In addition, exercises to help peripheral neuropathy, when done regularly, may reduce neuropathic pain and can help control blood sugar levels. Another option to release the nerve is to remove part of the medial epicondyle. Tip: As you perform this movement, engage your core and use your buttocks and hamstrings to help balance yourself. Capsaicin cream, which contains a substance found in hot peppers, can cause modest improvements in peripheral neuropathy symptoms. When considering any medication, talk to your health care provider about the benefits and possible side effects to find what might work best for you. Here are some examples of aerobic exercise: Flexibility exercises, also called stretching, help keep your joints flexible and reduce your chances of injury during other activities. https://www.foundationforpn.org/what-is-peripheral-neuropathy/symptoms/. There are several things that can cause pressure on the nerve at the elbow: Some factors put you more at risk for developing cubital tunnel syndrome. This article explains all you need to know about proprioception and offers 10 exercises you can try to improve it. https://www.niddk.nih.gov/health-information/diabetes/overview/preventing-problems/nerve-damage-diabetic-neuropathies/all-content. Proprioception is your bodys ability to sense where it is in space and adapt to sudden changes in the environment, such as those relating to force, tension, and body position. These sensors deliver information relating to changes in movement, position, tension, force, and environment to your brain (1, 2). Do this 812 times before switching sides. Mayo Clinic, Rochester, Minn. April 29, 2019. In severe cases, you may need to work with a trained specialist first. For example, do not drive with your arm resting on the open window. privacy practices. Slowly let them down. Peripheral neuropathy (adult). Peripheral neuropathy. In many cases of cubital tunnel syndrome, the exact cause is not known. If nonsurgical methods do not improve your symptoms, or if the nerve compression is causing muscle weakness or damage in your hand, your doctor may recommend surgery. 1) Toe Spreads Plant feet firmly on the floor. Anyone seeking specific orthopaedic advice or assistance should consult his or her orthopaedic surgeon, or locate one in your area through the AAOS Find an Orthopaedist program on this website. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Diabetic neuropathy and dietary supplements. Mayo Clinic. Hold position for 5-10 seconds. 2019; doi:10.1038/s41572-019-0092-1. The Foundation for Peripheral Neuropathy. Each method of surgery has a similar success rate for routine cases of nerve compression. Hinge your hips and bend your knees to lower into a. A submuscular transposition usually requires a longer time (3 to 6 weeks) in a splint. Several places along the nerve will be tested; the area where the response takes too long is likely to be the place where the nerve is compressed. Stay Within Your Limits https://www.uptodate.com/contents/search. Use lotion on your feet if they're dry. Accessed March 25, 2019. It also controls most of the little muscles in the hand that help with fine movements, and some of the bigger muscles in the forearm that help you make a strong grip. Numbness and tingling in the hand and fingers are common symptoms of cubital tunnel syndrome. Research has shown that strengthening exercises for peripheral neuropathy moderately improve muscle strength in people with PN. Accessed March 25, 2019. Stand on your left foot and lift your right foot in front of you a few inches off of the ground. But you can often prevent diabetic neuropathy or slow its progress with consistent blood sugar management and a healthy lifestyle. All rights reserved. What types of side effects can I expect from treatment? It can also cause problems with the digestive system, urinary tract, blood vessels and heart. 2 Repetitions/2 times a day. Slowly press up with your legs to standing. How can I best manage them together? About OrthoInfoEditorial Board Our ContributorsOur Subspecialty Partners Contact Us, Privacy PolicyTerms & Conditions Linking Policy AAOS Newsroom Find an FAAOS Surgeon. What might help you manage your diabetes better? Proprioception is your bodys ability to sense its movements, locations, and actions. Here are 10 at-home exercises to improve your proprioception. Gentle stretching for 5 to 10 minutes helps your body warm up and get ready for aerobic activities such as walking or swimming. American Diabetes Association. Peripheral neuropathy has many potential causes. Complementary and alternative medicine for painful peripheral neuropathy. https://www.niddk.nih.gov/health-information/diabetes/overview/preventing-problems/foot-problems#healthyfeet. Stand with your feet hip-width apart and your hands on your hips. Accessed Jan. 10, 2020. In many cases, the nerve is moved from its place behind the medial epicondyle to a new place in front of it. Mayo Clinic. Moving the nerve to the front of the medial epicondyle prevents it from getting caught on the bony ridge and stretching when you bend your elbow. Symptomatic treatment is usually necessary to relieve discomfort or pain. The first, and most important is to get glucose levels under control, as this is the main underlying reason for the condition. This content does not have an English version. Your ability to balance comes from three sensory inputs: the vestibular system (motion, equilibrium, and spatial orientation), vision (eyesight), and proprioception (touch) (12, 13, 14). Stand in this position for 30 seconds and switch sides. Its a critical sense to help with balance and movement. Stand straight, directly behind chair or table, feet slightly apart. For most people, its best to aim for a total of about 30 minutes a day, between 3-5 days a week. Copyright 1995-2021 by the American Academy of Orthopaedic Surgeons. Does anyone in your family have symptoms similar to yours? Ulnar nerve entrapment occurs when the ulnar nerve in the arm becomes compressed or irritated. Stand on one foot with your hands on your hips and a cone 2 feet (about 60 cm) in front of you. All neuropathies require medical attention because they will worsen without treatment. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Following the Foundation for Peripheral Neuropathys (FPN) recent webinar on current research trends, Lindsay Colbert, FPNs Executive Director, caught up with the programs panelists, Dr. Diabetic neuropathy. Various therapies and procedures might help ease the signs and symptoms of peripheral neuropathy. National Institute of Diabetes and Digestive and Kidney Diseases. AskMayoExpert. This illustration shows the path of the ulnar nerve through the cubital tunnel. information is beneficial, we may combine your email and website usage information with You should feel a muscle stretch in the bottom of your foot and along your heel cord. Some antidepressants ease nerve pain, even if you aren't depressed. These exercises may also help prevent stiffness in the arm and wrist. Then, repeat the movement to return the cone to its original starting point. Your symptoms can flare up due to a variety of triggers. AAOS does not endorse any treatments, procedures, products, or physicians referenced herein. health information, we will treat all of that information as protected health Bend your right knee outward and place your right foot on your left inner thigh. Ulnar nerve compression at the elbow is called cubital tunnel syndrome. 25th ed. If you have been diagnosed with neuropathy, it may be concerning. Make a donation. The main purpose is to prevent injury by increasing spatial awareness and balance. Physicians in Taiwan have published a new study that finds that getting active may actually help alleviate some pain, including that related to nerve damage. Differences Between Peripheral Neuropathy and MS, Causes and Risk Factors of Diabetic Neuropathy. Over-the-counter pain medications, such as nonsteroidal anti-inflammatory drugs, can relieve mild symptoms. Advertising revenue supports our not-for-profit mission. WebIt usually involves weakness followed by wasting of muscles, and excruciating pain in the muscles of the thigh, hip, and buttocks. These nerves control movement of the intestines, heart rate, strength of heart contraction, blood pressure, urination, and more. Elsevier; 2022. https://www.clinicalkey.com. While facing a door frame, place your heel as close to the door frame as possible. Accessed April 2, 2019. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. It's the most common type of diabetic neuropathy. Review/update the The, Falls are the most common cause of injury in elderly adults (age 65 and older). Hypothyroidism: Can it cause peripheral neuropathy? Improving proprioception in the muscles, tendons, and joints can help an athlete adapt to quick movements or shifts in balance to prevent common injuries and reinjuries like ankle sprains (7, 8, 9). WebNerve gliding exercises. Dr. Moawad regularly writes and edits health and career content for medical books and publications. Alternatively, use a long piece of string or rope. In: Goldman-Cecil Medicine. I have other health conditions. If you struggle with balance, you may wish to be near a wall or have a partner for support. Fortunately, adding proprioception training exercises to your routine can lower your risk of injury and improve your fitness levels. Ferri FF. Sitting on the front half of a firm chair, place one leg out straight with the foot pointing up. Your symptoms depend on the type you have and which nerves are affected. Repeat: 3 repetitions each leg/2 times a day. Disorders of peripheral nerves. Imagine that youre new to basketball. Ultimately, training your balance and proprioception is important for reducing your risk of injury and falls while also improving your athletic performance. A single copy of these materials may be reprinted for noncommercial personal use only. The ulnar nerve is one of the three main nerves in your arm. These procedures are most often done on an outpatient basis, but some patients do best with an overnight stay at the hospital. Once this happens, muscle wasting cannot be reversed. Lift yourself back up until youre in the starting position. Here's information to help you prepare for your appointment. Feldman EL, et al. Whats more, another study showed greater proprioception is highly correlated with athletic abilities, with elite athletes demonstrating the greatest levels of proprioception in the ankles, shoulder, and spine (11). Repeat with other leg. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Some people with peripheral neuropathy try complementary treatments for relief. The pain of neuropathy can be distressing, and it can interfere with your quality of life and with your ability to be active. The ulnar nerve gives feeling to the little finger and half of the ring finger. The feeling of "falling asleep" in the ring finger and little finger, especially when your elbow is bent. health information, we will treat all of that information as protected health Read our. In this surgical photo, a cubital tunnel release has been performed to decompress, or relieve pressure on, the ulnar nerve. Slowly lean forward, allowing your heel to slide back as your toes extend upward. The Foundation for Peripheral Neuropathy. Accessed Dec. 17, 2021. Besides medications used to treat conditions associated with peripheral neuropathy, medications used to relieve peripheral neuropathy signs and symptoms include: Pain relievers. Drugs in this class include amitriptyline, nortriptyline (Pamelor) and desipramine (Norpramin). Jankovic J, et al., eds. There is a problem with To manage complications, you may need care from different specialists. If your symptoms interfere with normal activities or last more than a few weeks, be sure to schedule an appointment with your doctor. A1C goals may need to be individualized, but for many adults, the ADA recommends an A1C of less than 7.0%. Hold: 5-10 seconds If you do not experience any pain, you can start using a weight while doing this exercise. The ADA offers online support through its website. You may not notice anything is wrong until considerable nerve damage has occurred. Usually, treatment of neuropathy is focused on preventing nerve and myelin damage by controlling the underlying cause. Neuropathy can affect different nerves throughout the body, usually with a specific pattern of involvement. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Diabetes Care. Our caring team of Mayo Clinic experts can help you with your peripheral neuropathy-related health concerns This is commonly called "hitting your funny bone. If you are a Mayo Clinic patient, this could Electromyography (EMG) records electrical activity in your muscles to detect nerve damage. 2021. https://care.diabetesjournals.org/content/44/Supplement_1. Diabetic neuropathy. Older muscles are smaller and slower and respond less efficiently when you need to brace yourselves, making you more vulnerable to falls. Aim for 150 minutes of moderate or 75 minutes of vigorous aerobic activity a week, or a combination of moderate and vigorous exercise. Baute V, et al. Place one foot on the line or beside the rope. Bend at hips; hold onto chair or table. Nature Reviews Disease Primers. I have other health conditions. al. Tape a straight line about 36-feet (12-meters) long on the floor. Autonomic neuropathy and proximal neuropathy affect larger nerves and can cause substantial symptoms. Is this condition temporary or long lasting? What's the most likely cause of my symptoms? Here, we share Robert Herricks tip on the simple. The Foundation serves as a leading resource for advancing collaborative and innovative therapeutic developments and accelerating the ability to diagnose, treat, prevent and cure peripheral neuropathy. See which power racks our team has picked for you to ensure that you get the most out of your home gym. Most of the symptoms, however, occur in your hand.

Kali Flanagan Back To The Start, Oscar Goodman Health, Top 50 Worst Cities In California, Articles P

proximal neuropathy exercises