senile purpura and alcohol
Terms of Use. Enter search terms to find related medical topics, multimedia and more. The size and distribution of purpura are usually determined by what's causing them. Philadelphia, Pa.: Elsevier; 2020. https://www.clinicalkey.com. 2006 Feb;28(2):222-35. doi: 10.1016/j.clinthera.2006.02.004. For example, if purpura is related to a blood clotting disorder or low platelet levels, it can put your life at risk. Dosage of drugs is not considered in the study. Purpura refers to purplish cutaneous or mucosal lesions caused by hemorrhage. They may represent severe emotional or psychiatric disturbance. Never give an intramuscular (IM) injection if a serious bleeding disorder is suspected, or a very painful haematoma will develop. Also tell him what medicines or supplements you take. Clin Pediatr (Phila). Senile Purpura And Purpura Simplex Most commonly, easy or excessive bruising occurs because the skin and blood vessels are fragile. The spots appear differently depending on your skin tone. Your blood thinner, aspirin, or other medicine may need to be stopped or changed. When blood vessels get inflamed, they can bleed into the skin, causing a reddish-purple rash (purpura). Be guided by your findings so far. "Zinc deficiency in senile purpura". Purpura may occur with either normal platelet counts (non-thrombocytopenic purpuras) or decreased platelet counts (thrombocytopenic purpuras). Despite being a benign condition, the continual development of purpura lesions in afflicted patients is frequently a source of significant visual and social concern. What Is Idiopathic Thrombocytopenic Purpura (ITP)? Leukaemia or related diseases may produce anaemia and leukocytopenia. Linkins LA. You have blood in your urine or bowel movement. Senile purpura may also be a sign of collagen loss in skin and bone. The phase IV clinical study analyzes which people take Alcohol and have Purpura. Purpura happen when blood leaks from blood vessels and collects under the skin or mucus membrane. government site. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. See additional information. Before Having inspected the skin and taken a history, it may be useful to return to a physical examination to reassess the purpuric rash and carry out a further systemic examination, looking for hepatomegaly/splenomegaly or neurological signs, for example. Anyone can get purpura. Bleeding underneath the skin causes tiny red or purple dots called petechiae. Although it is a common and clinically important condition, only a few studies have described in detail the clinical features or factors related to senile purpura 3 . Purpura fulminans is a rare but potentially life-threatening disorder, proving fatal in up to 50% of cases. The information on this page is written and peer reviewed by qualified clinicians. All rights reserved. Lesions are usually more than 3 mm in diameter and commonly present on the surface of the hands but do not extend onto the fingers. Purpura is between 4 millimeters (mm) and 10 mm in diameter. Warfarin may be used to clear up blood clots. National Heart, Lung, and Blood Institute. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. The platelet count is fundamental. Bateman's Purpura is Common Bruising Beneath the Skin of the Elderly The condition known as Bateman's Purpura, otherwise known as senile purpura, is a common one among senior citizens. Purpura all over the body is one sign of disseminated intravascular coagulation. This is due to a low number of blood cell fragments called platelets. That leads to low levels. 34 ratings. Purpura can be a sign of a serious illness. The asymptomatic purpura was limited to both lower limbs, self-limiting with abstinence, and reoccurring swiftly with alcohol relapse. International J Pharm and Pharm Sci. Different individuals may respond to medication in different ways. Patients develop persistent dark purple ecchymoses . Senile purpura is benign, easy bruising that affects older adults. Boynton Beach, Fla. - A new experimental oral medication known as Purpurex (New Vitality) is effective in improving and even clearing the appearance of senile purpura, while helping to prevent new lesions from occurring, according to a recent study. Crookston K et al; Acquired bleeding disorders: Amyloidosis, PathologyOutlines.com, 2010. For details see our conditions. doi: 10.1067/mjd.2000.104512. No adverse effects were noted by either the patients or investigators. Nonthrombocytopenic purpura often doesn't need to be treated. Last updated on Feb 6, 2023. Oye M, Alkhasawneh A, Quan JR. Gamma-Delta Large Granular Lymphocytic Leukemia: A Diagnostic Dilemma. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. This will be guided by the differential diagnosis, much of which will already have been excluded. For example, localised lesions may be caused by trauma whereas purpura due to venous hypertension will be in the lower legs with a distribution as shown below. Purpura is reported only by a few people who take Alcohol. 8. J Am Acad Dermatol. Efficacy and safety of mixed amphetamine salts extended release (Adderall XR) in the management of attention-deficit/hyperactivity disorder in adolescent patients: a 4-week, randomized, double-blind, placebo-controlled, parallel-group study. Hahn D, Hodson EM, Willis NS, et al; Interventions for preventing and treating kidney disease in Henoch-Schonlein Purpura (HSP). Heparin induced thrombocytopenia: diagnosis and management update. The main types of purpura are defined by whether platelets are involved. Spencer TJ, Wilens TE, Biederman J, Weisler RH, Read SC, Pratt R. Clin Ther. Bruises, either single or multiple, appear spontaneously, mainly on arms or legs, and resolve without any specific treatment. Patients were randomized to receive either Purpurex, which consists of a nutraceutical citrus bioflavonoid blend (CBB) of ingredients, or placebo (calcium carbonate) twice daily in oral form for six weeks. In persistent or chronic cases, treatments may include: In some cases, an underlying infection may be treated. All rights reserved. MedicineNet does not provide medical advice, diagnosis or treatment. Temple AR, Benson GD, Zinsenheim JR, Schweinle JE. Senile purpura typically affects older patients as their dermal tissues atrophy and blood vessels become more fragile. Residual hemosiderosis (iron deposition) in the affected area may occur. It is due to the production of an antibody to a specific platelet antigen that the woman normally lacks. If a blood clotting disorder is causing the purpura, it could cause severe or fatal bleeding. 2020;102(4):229-233. It can be hard to stop bleeding from cuts and scrapes. information submitted for this request. Actinic purpura results from sun-induced damage to the connective tissue of the dermis (deeper layers of the skin) combined with the fact that the blood vessels become thinner and more fragile and collagen decreases with increasing age. 2018;10(1):211213. information and will only use or disclose that information as set forth in our notice of "Patients with senile purpura (SP) tend to bruise very easily and develop ecchymoses appearing most commonly on the extensor surfaces of the forearms, legs and hands following suspected trauma to those areas. This condition develops as the blood vessels become fragile due to age leading to easy bruising with even minor falls causing significant bruises. Small lesions (< 2 mm) are termed petechiae, and large lesions are termed ecchymoses or bruises. the unsubscribe link in the e-mail. Cookies collect information about your preferences and your devices and are used to make the site work as you expect it to, to understand how you interact with the site, and to show advertisements that are targeted to your interests. There may be associated acute arthritis, gastrointestinal pain and nephritis with proteinuria. Some medications can cause purpura, including blood-thinning drugs like Coumadin (warfarin) or aspirin. Selective reduction in megakaryocytes (eg, drugs such as co-trimoxazole, chemicals, viral infections). 2022 Jan 2;14(1):e20883. You may opt-out of email communications at any time by clicking on There is a problem with NICE has issued rapid update guidelines in relation to many of these. Case presentation: Shtalrid M, Shvidel L, Vorst E, et al; Post-transfusion purpura: a challenging diagnosis. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. It sounds like you have senile purpura, a very common and harmless condition. Phellodendron and Citrus extracts benefit joint health in osteoarthritis patients: a pilot, double-blind, placebo-controlled study. This may be considered where there are episodes of inexplicable bleeding/bruising. During the last 2 years of that period, purpuric rashes were newly observed. A single copy of these materials may be reprinted for noncommercial personal use only. Assess your symptoms online with our free symptom checker. and transmitted securely. You have questions or concerns about your condition or care. Our doctors define difficult medical language in easy-to-understand explanations of over 19,000 medical terms. In children, often following a viral infection like chickenpox, the ITP usually goes away without treatment. Spots less than 4 millimeters (mm) in diameter are called petechiae. 8600 Rockville Pike In the multicenter, randomized, placebo-controlled, double-blind study, 70 patients with SP were enrolled, of which 67 completed the trial. The skin may appear darker due to hyperpigmentation as a result of residual hemosiderosis. Purpura is more likely to appear in the mouth's inner lining. Accessed May 13, 2019. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). There are many different types of purpura. The purpuric rash may continue to form over several weeks. senile purpura and alcohol. If your child develops the rash associated with this condition, see your doctor as soon as possible. Some cases of IgA vasculitis are severe or include kidney damage. Am Fam Physician. Senile purpura causes ecchymoses and results from increased vessel fragility due to connective tissue damage or atrophy in the dermis caused by chronic sun exposure, aging, and drugs. Posted by ellerbracke @ellerbracke, May 24, 2019 . Joint pain may be treated with anti-inflammatory and cortisone medications. Maher GM; Immune thrombocytopenia. Purpura refers to purple bruises caused by bleeding under the skin. Theyll discuss your medical history and any drugs or medications youre taking. Aging (senile purpura)* Dark ecchymosis in aged, thin skin; typically over extensor surfaces of forearms: Glucocorticoids* Patients at risk with long-term use (eg, polymyalgia rheumatica) Alcohol abuse* History of heavy alcohol intake; signs of cirrhotic liver disease: Wasting, malnutrition* Dietary history, cachetic on examination Keywords: Are dark blue spots on my skin related to purpura? Philadelphia, Pa.: Elsevier; 2019. https://www.clinicalkey.com. Those patients receiving Purpurex showed a 19 percent, 29 percent and 50 percent decrease in purpura lesions at weeks two, four and six, respectively. doi: 10.1111/j.1365-4362.1983.tb02188.x. National Institutes of Health, National Heart, Lung, and Blood Institute. Both primary and secondary amyloid can cause purpura that is known as 'pinch purpura' because of the typical appearance on the cheeks. Can you pronounce this word better. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). -, Smith KE, Fenske NA. It's also more common in boys than girls. Otherwise, senile and IgA vasculitis-related cases usually go away on their own. As a general rule, purpura indicates a problem of the platelet system whilst a deficiency of clotting factors will cause haematomas or haemarthrosis as in haemophilia. Sometimes, treatment isnt needed and the purpura goes away on its own. Patients develop persistent dark purple ecchymoses, which are characteristically confined to the extensor surfaces of the hands and forearms. It is. The use of the eHealthMe site and its content is at your own risk. That child may be moribund just 20 minutes later. Instead, they're tied to more serious conditions. University of Michigan Health, Michigan Medicine. Very difficult. Senile purpura is a common, chronic skin condition affecting more than 10 percent of individuals over the age of 50. It's not clear why this initial inflammation develops. Idiopathic means that the cause of the condition isn't known. It is caused by atrophy of the collagen fibres supporting blood vessels in the skin. Other drugs that have the same active ingredients (e.g. Semin Fetal Neonatal Med. Other components of a routine history should be gone through (past medical history, medical and allergic history - including any over-the-counter drugs - and social history are all relevant). 2006 Oct8(10):672-4. Purpura can indicate a platelet count below 30 x 10. The term 'purpura' describes a purplish discolouration of the skin that is produced by small bleeding vessels near the surface. 2003 Jan;48(1):31-3. doi: 10.1067/mjd.2003.25. Weakened blood vessels from age or sun exposure. sharing sensitive information, make sure youre on a federal Its a sign of something else. Cochrane Database Syst Rev. If we combine this information with your protected Henoch-Schonlein purpura. For DIC, the cause of purpura needs to be treated. Purpura larger than 1 centimeter (cm) is called ecchymoses (or bruises). Discuss ways to help you cope with purpura (such as covering up the spots). Moderate. This type of purpura happens when our blood vessels become weak. Cox NH, Piette WW. There are different types of purpura. doi:10.22159/ijpps.2018v10i1.22212. Its common for petechiae to resemble a rash because the dots are tiny and tend to cluster. Factors that increase the risk of developing Henoch-Schonlein purpura include: For most people, symptoms improve within a month, leaving no lasting problems. Fair skinned older people are more likely to develop the condition. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Family Health Book, 5th Edition, Newsletter: Mayo Clinic Health Letter Digital Edition. Idiopathic thrombocytopenic purpura (ITP) is a bleeding condition in which the blood doesn't clot as it should. Torrelo A, Requena C, Mediero IG, Zambrano A. J Am Acad Dermatol. The management of the various diseases is found in the respective articles. Oxford: Wiley-Blackwell; 2010. p. 49.1. It is unusual for purpura to emerge as a result of drinking alcohol. This is caused by inflammation and infiltration of the blood vessel wall as an anaphylactic reaction to a number of physical and chemical stimuli, including infections. Pigmented Purpuric Dermatoses: A Complete Narrative Review. Results: "We believe that the steady decrease in the number of purpura lesions is due to a cumulative pharmacological effect of the supplement, the ingredients of which work synergistically to improve the appearance of SP and prevent new lesions from forming," Dr. Berlin says. It usually follows a respiratory illness, such as strep throat, but the exact cause is unknown. Nevertheless, clotting factor deficiency must be considered. National Library of Medicine. National Institute of Health. Predisposing factors include the influence of ultraviolet radiation, anticoagulant therapy. You may need blood tests to count your platelets or time how fast your blood clots. They're usually quite serious and require immediate treatment. Treatment options include: Patients are advised to try and avoid any risk of injury to the affected areas. It can be. Despite being a benign condition, the continual development of purpura lesions in afflicted patients is frequently a source of significant visual and social concern. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Use for phrases It is created by eHealthMe based on reports of 18,201 people who have side effects while taking Alcohol from the FDA, and is updated regularly. Purpura, also known as skin hemorrhages or blood spots, can signal several medical problems, ranging from minor injuries to life threatening infections. 2019 Aug;31(4):472-475. doi: 10.5021/ad.2019.31.4.472. The cause is not known. If purpura is caused by an infection, you may have a fever or pain in the infected body part. Before each of the four treatments, and 1 month after the last treatment, the subjects' number and square area of ecchymoses will be measured by an evaluator and . Its common in older adults. Record the pronunciation of this word in your own voice and play it to listen to how you have pronounced it. You have irregular or heavy menstrual bleeding. Once your healthcare provider determines the discolored skin spots are purpura, they must determine whats causing it. Small lesions (< 2 mm) are termed petechiae, and large lesions are termed ecchymoses or bruises. Think of these in chronic cases. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Schamberg's disease induction by vinegar may point to an involvement of acetate, a metabolite of ethanol. Warfarin-induced skin necrosis starts with purpura, then progresses to: This condition most often affects specific areas of the body. Registered in England and Wales. Thrombocytopenic purpura is caused by low platelets in the blood. How to Increase Your Platelet Count Naturally, The Function of Blood Platelets or Thrombocytes. Reamy BV, Servey JT, Williams PM. Establish whether the patient is otherwise well. Senile purpura is different than conditions that cause easy bruising, due to bleeding disorders. Some types of vasculitis: Vasculitis may cause purpura through inflammation of the blood vessels in the skin, gastrointestinal tract, and kidneys. This content does not have an Arabic version. You may notice them on your skin or mucous membranes (e.g., inside your mouth). A blood test will reveal a low platelet level. Yes, purpura can resemble a rash or bruise. Purpura (purplish discoloration of the skin) is found to be associated with 1,814 drugs and 1,420 conditions by eHealthMe. To provide you with the most relevant and helpful information, and understand which Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. Easy. A skin biopsy revealed histological features of purpura pigmentosa progressiva (termed Schamberg's disease). Until now, no effective treatments have been available to address the condition, let alone help prevent future lesions from occurring," says Joshua M. Berlin, M.D., Dermatology Associates P.A., Boynton Beach, Fla. Dr. Berlin recently conducted a clinical trial evaluating the efficacy and safety of Purpurex in improving the skin's appearance in patients with SP. The others include: You may also have redness or a rash where the heparin was administered. Allergic causes such as Henoch-Schnlein purpura, connective tissue disorders (eg. In: Burns T, Breathnach S, Cox N, Griffiths C, editors. At the six-week follow up, a 50 percent reduction in the purpura lesions from baseline was seen in those patients receiving Purpurex, compared to a 9 percent increase in purpura lesions in the placebo group. An adult Caucasian alcohol-dependent patient who developed purpura after drinking alcohol was clinically observed from May 2005 to April 2016 at our institution (Table 1).The last 2 years ("purpuric phase"; cf. Purpura is a physical sign of an. Usually, the focus of treatment isn't the purpura itself, but the underlying condition that triggered it. Heparin-induced thrombocytopenia needs immediate treatment. Senile purpura is a prevalent non-cancerous condition marked by recurrent development of purplish bruises or ecchymoses on the extensor surface of the arms, usually after some kind of mild trauma. A similar appearance is also found in senile-type purpura. a There is a light perivascular lymphocytic infiltration, MeSH Platelets help your blood clot and prevent severe bleeding. Even with wearing long sleeves while working outside, (today it was about 76 degrees by 8 AM here), I still get poked or scratched. Actinic purpura could be an indication of osteoporosis, a sign of collagen loss in the skin and bone. 2020. If you are a Mayo Clinic patient, this could An official website of the United States government. 9500 Euclid Avenue, Cleveland, Ohio 44195 |, Important Updates + Notice of Vendor Data Event. 2018 Jan;11(1):13-18. Federal government websites often end in .gov or .mil. Saulsbury FT; Henoch-Schonlein purpura. Johns Hopkins Medicine. HSP often resolves on its own. It happens when small blood vessels leak blood under your skins surface. Leah Ansell, MD, is a board-certified dermatologist and an assistant professor of dermatology at Columbia University. Purpura refers to purplish cutaneous or mucosal lesions caused by hemorrhage. Some of these changes can include: bones shrinking in size or becoming weaker. Why do steroids cause purpura? Causes of nonthrombocytopenic purpura can include: Senile purpura is caused by thinning and weakening skin and blood vessels. By Carrie Madormo, RN, MPH Our expert physicians and surgeons provide a full range of dermatologic, reconstructive and aesthetic treatments options at Cleveland Clinic. Am Fam Physician. These include: Chemotherapy drugs can damage platelets, as well. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. These include Tylenol (acetaminophen) and Advil/Motrin (ibuprofen). The resulting bleeds and the bruises are way out of proportion to the cause. You can find out more about our use, change your default settings, and withdraw your consent at any time with effect for the future by visiting Cookies Settings, which can also be found in the footer of the site. In adults, purpura is usually a sign of an underlying condition but can also resolve without treatment. 2009 Sep-Oct26(5):597-600. Most people dont experience itching or painful purpura. Other anticoagulants like aspirin may be used as well. Poor blood vessel health (weak, fragile or inflamed blood vessels). They look red or purple on lighter skin tones but appear brown or black on darker skin tones. The .gov means its official. Patients were assessed at baseline, two, four and six weeks. In: Kitchens CS, Kessler CM, Konkle BA, Streiff MB, Garcia DA, eds. In: StatPearls [Internet]. It is due to the production of an antibody to a specific platelet antigen that the woman normally lacks. Click here for an email preview. -, Therapondos G, Delahooke TE, Hayes PC. splenectomy: does it still play a role in the management of thrombotic thrombocytopenic purpura? Tell him about any health condition you have that causes bleeding. Some lesions are darker than others because of their longer duration. Contact your healthcare provider if you notice purpura or any blood spots, patches or skin discoloration. Careers. Larger, deeper purpura are referred to as ecchymoses or bruising. 2022 Aug 8. These appear as multiple lesions, often symmetrically involving distal extremities, areas of pressure and lips, ears, nose and trunk. What do you know about the Sun and the damage it can cause to our skin. Mayo Clinic is a not-for-profit organization. Bruises and blood spots under the skin. Please visit https://www.nice.org.uk/covid-19 to see if there is temporary guidance issued by NICE in relation to the management of this condition, which may vary from the information given below. Some blood cancers (lymphomas and leukemias) can cause low levels of platelets. If the purpura spot is less than 4 mm wide, its called petechiae. Unauthorized use of these marks is strictly prohibited. The cause of purpura depends on the type. Senile purpura typically affects older patients as their dermal tissues atrophy and blood vessels become more fragile. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. Acetate; Alcohol; Hypersensitivity-like reaction; Purpura; Schambergs disease. Nonthrombocytopenic purpura (NTP) involves bleeding due to alterednot lowplatelet function or inflammation. Federal government websites often end in .gov or .mil. If a child has developed a purpuric, possibly meningococcal, rash but does not seem unwell, do not be lured into a false sense of security. Tenderness may suggest an inflammatory process. sharing sensitive information, make sure youre on a federal Senile Purpura: Clinical Features and Related Factors. National Institutes of Health, U.S. National Library of Medicine: MedlinePlus. If the patient is on warfarin, check INR. Determine how long the rash has been present and whether it is changing noticeably. Women have lesser collagen than men; hence, its slightly more common in women than in men. Henoch-Schonlein purpura (also known as IgA vasculitis) is a disorder that causes the small blood vessels in your skin, joints, intestines and kidneys to become inflamed and bleed. There is a sharp demarcation (margin) seen between the borders of the lesions and normal surrounding skin. A person with nonthrombocytopenic purpura has platelet levels in a normal range. Bookshelf Efficacy and tolerability of sustained-release tramadol in the treatment of symptomatic osteoarthritis of the hip or knee: a multicenter, randomized, double-blind, placebo-controlled study. American Family Physician. To evaluate the efficacy of a novel nutraceutical citrus bioflavonoid blend in improving the skin's appearance in patients with senile purpura. No treatment hastens lesion resolution or is needed. a decrease in flexibility, strength, or endurance. Rooks textbook of dermatology. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. Purpura. Idiopathic Thrombocytopenic Purpura. Bruises heal on their own over the course of two to four weeks. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. It's sometimes called actinic purpura. Read our editorial policy. Immunologic disturbances thereby acquired could have constituted a basis for a hypersensitivity-like reaction after ingestion of alcohol. Brought to you by Merck & Co, Inc., Rahway, NJ, USA (known as MSD outside the US and Canada) dedicated to using leading-edge science to save and improve lives around the world. All information is observation-only. 2010 Sep22(5):598-602. Henoch-Schonlein purpura is an inflammation of the small blood vessels of the skin, joints, bowels and kidneys. vol. We comply with the HONcode standard for trustworthy health information. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Henoch-Schonlein purpura (also known as IgA vasculitis) is a disorder that causes the small blood vessels in your skin, joints, intestines and kidneys to become inflamed and bleed. 1987 Dec;26(12):659-61. doi: 10.1177/000992288702601210. Cureus. It is often preceded by an upper respiratory tract infection due to beta-haemolytic streptococcal infection. Coming to a Cleveland Clinic location?Hillcrest Cancer Center check-in changesCole Eye entrance closingVisitation, mask requirements and COVID-19 information, Notice of Intelligent Business Solutions data eventLearn more. Treasure Island (FL): StatPearls Publishing; 2022 Jan. eHealthMe is studying from 18,442 Alcohol users for its effectiveness, alternative drugs and more. Acquired causes such as severe infections (eg. Intravenous immunoglobin (IVIG) treatments to raise platelet levels fast. Authors Soo Ick Cho 1 . Unable to load your collection due to an error, Unable to load your delegates due to an error. If youre bleeding under your skin, it can appear as one larger patch (bruise) or several smaller dots (petechiae). Meanwhile, plasma transfusions and blood-thinning medication can help treat the symptoms. It is very nonspecific. Disseminated intravascular coagulation (DIC). Purpura is one of the first signs. Medline Plus. Long-term use of strong steroids can cause widespread purpura and bruising, normally on extensor surfaces of the hands, arms and thighs.